class Bio::UniProtKB

aalen()

Alias for: sequence_length

aaseq()

Alias for: seq

cc(topic = nil) click to toggle source

returns contents in the CC lines.

#cc -> Hash

returns an object of contents in the TOPIC.

#cc -> Array w/in Hash, Hash

returns contents of the “ALTERNATIVE PRODUCTS”.

#cc('ALTERNATIVE PRODUCTS') -> Hash

{'Event' => str, 
 'Named isoforms' => int,  
 'Comment' => str,
 'Variants'=>[{'Name' => str, 'Synonyms' => str, 'IsoId' => str, 'Sequence' => []}]}

CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=15;
...
CC         placentae isoforms. All tissues differentially splice exon 13;
CC       Name=A; Synonyms=no del;
CC         IsoId=P15529-1; Sequence=Displayed;

returns contents of the “DATABASE”.

#cc('DATABASE') -> Array

[{'NAME'=>str,'NOTE'=>str, 'WWW'=>URI,'FTP'=>URI}, ...]

CC   -!- DATABASE: NAME=Text[; NOTE=Text][; WWW="Address"][; FTP="Address"].

returns contents of the “MASS SPECTROMETRY”.

#cc('MASS SPECTROMETRY') -> Array

[{'MW"=>float,'MW_ERR'=>float, 'METHOD'=>str,'RANGE'=>str}, ...]

CC   -!- MASS SPECTROMETRY: MW=XXX[; MW_ERR=XX][; METHOD=XX][;RANGE=XX-XX].

CC lines (>=0, optional)¶ ↑

CC   -!- TISSUE SPECIFICITY: HIGHEST LEVELS FOUND IN TESTIS. ALSO PRESENT
CC       IN LIVER, KIDNEY, LUNG AND BRAIN.

CC   -!- TOPIC: FIRST LINE OF A COMMENT BLOCK;
CC       SECOND AND SUBSEQUENT LINES OF A COMMENT BLOCK.

# File lib/bio/db/embl/uniprotkb.rb, line 774
def cc(topic = nil)
  unless @data['CC']
    cc  = Hash.new
    comment_border= '-' * (77 - 4 + 1)
    dlm = /-!- /

    # 12KD_MYCSM has no CC lines.
    return cc if get('CC').size == 0
    
    cc_raw = fetch('CC')

    # Removing the copyright statement.
    cc_raw.sub!(/ *---.+---/m, '')

    # Not any CC Lines without the copyright statement.
    return cc if cc_raw == ''

    begin
      cc_raw, copyright = cc_raw.split(/#{comment_border}/)[0]
      _ = copyright #dummy for suppress "assigned but unused variable"
      cc_raw = cc_raw.sub(dlm,'')
      cc_raw.split(dlm).each do |tmp|
        tmp = tmp.strip

        if /(^[A-Z ]+[A-Z]): (.+)/ =~ tmp
          key  = $1
          body = $2
          body.gsub!(/- (?!AND)/,'-')
          body.strip!
          unless cc[key]
            cc[key] = [body]
          else
            cc[key].push(body)
          end
        else
          raise ["Error: [#{entry_id}]: CC Lines", '"', tmp, '"',
                 '', get('CC'),''].join("\n")
        end
      end
    rescue NameError
      if fetch('CC') == ''
        return {}
      else
        raise ["Error: Invalid CC Lines: [#{entry_id}]: ",
               "\n'#{self.get('CC')}'\n", "(#{$!})"].join
      end
    rescue NoMethodError
    end
    
    @data['CC'] = cc
  end


  case topic
  when 'ALLERGEN'
    return @data['CC'][topic]
  when 'ALTERNATIVE PRODUCTS'
    return cc_alternative_products(@data['CC'][topic])
  when 'BIOPHYSICOCHEMICAL PROPERTIES'
    return cc_biophysiochemical_properties(@data['CC'][topic])
  when 'BIOTECHNOLOGY'
    return @data['CC'][topic]
  when 'CATALITIC ACTIVITY'
    return cc_catalytic_activity(@data['CC'][topic])
  when 'CAUTION'
    return cc_caution(@data['CC'][topic])
  when 'COFACTOR'
    return @data['CC'][topic]
  when 'DEVELOPMENTAL STAGE'
    return @data['CC'][topic].join('')
  when 'DISEASE'
    return @data['CC'][topic].join('')
  when 'DOMAIN'
    return @data['CC'][topic]
  when 'ENZYME REGULATION'
    return @data['CC'][topic].join('')
  when 'FUNCTION'
    return @data['CC'][topic].join('')
  when 'INDUCTION'
    return @data['CC'][topic].join('')
  when 'INTERACTION'
    return cc_interaction(@data['CC'][topic])
  when 'MASS SPECTROMETRY'
    return cc_mass_spectrometry(@data['CC'][topic])
  when 'MISCELLANEOUS'
    return @data['CC'][topic]
  when 'PATHWAY'
    return cc_pathway(@data['CC'][topic])
  when 'PHARMACEUTICAL'
    return @data['CC'][topic]
  when 'POLYMORPHISM'
    return @data['CC'][topic]
  when 'PTM'
    return @data['CC'][topic]
  when 'RNA EDITING'
    return cc_rna_editing(@data['CC'][topic])
  when 'SIMILARITY'
    return @data['CC'][topic]
  when 'SUBCELLULAR LOCATION'
    return cc_subcellular_location(@data['CC'][topic])
  when 'SUBUNIT'
    return @data['CC'][topic]
  when 'TISSUE SPECIFICITY'
    return @data['CC'][topic]
  when 'TOXIC DOSE'
    return @data['CC'][topic]
  when 'WEB RESOURCE'
    return cc_web_resource(@data['CC'][topic])
  when 'DATABASE'
    # DATABASE: NAME=Text[; NOTE=Text][; WWW="Address"][; FTP="Address"].
    tmp = Array.new
    db = @data['CC']['DATABASE']
    return db unless db

    db.each do |e|
      db = {'NAME' => nil, 'NOTE' => nil, 'WWW' => nil, 'FTP' => nil}
      e.sub(/.$/,'').split(/;/).each do |line|
        case line
        when /NAME=(.+)/
          db['NAME'] = $1
        when /NOTE=(.+)/
          db['NOTE'] = $1
        when /WWW="(.+)"/
          db['WWW'] = $1
        when /FTP="(.+)"/
          db['FTP'] = $1
        end 
      end
      tmp.push(db)
    end
    return tmp
  when nil
    return @data['CC']
  else
    return @data['CC'][topic]
  end
end

dr(key = nil) click to toggle source

#dr

# File lib/bio/db/embl/uniprotkb.rb, line 1131
def dr(key = nil)
  unless key
    embl_dr
  else
    (embl_dr[key] or []).map {|x|
      {'Accession' => x[0],
       'Version' => x[1],
       ' ' => x[2],
       'Molecular Type' => x[3]}
    }
  end
end

Also aliased as: embl_dr

dt(key = nil) click to toggle source

returns a Hash of information in the DT lines.

hash keys: 
  ['created', 'sequence', 'annotation']

Since UniProtKB release 7.0 of 07-Feb-2006, the DT line format is changed, and the word “annotation” is no longer used in DT lines. Despite the change, the word “annotation” is still used for keeping compatibility.

returns a String of information in the DT lines by a given key.

DT Line; date (3/entry)¶ ↑

DT DD-MMM-YYY (integrated into UniProtKB/XXXXX.)
DT DD-MMM-YYY (sequence version NN)
DT DD-MMM-YYY (entry version NN)

The format have been changed in UniProtKB release 7.0 of 07-Feb-2006. Below is the older format.

Old format of DT Line; date (3/entry)¶ ↑

DT DD-MMM-YYY (rel. NN, Created)
DT DD-MMM-YYY (rel. NN, Last sequence update)
DT DD-MMM-YYY (rel. NN, Last annotation update)

# File lib/bio/db/embl/uniprotkb.rb, line 157
def dt(key = nil)
  return dt[key] if key
  return @data['DT'] if @data['DT']

  part = self.get('DT').split(/\n/)
  @data['DT'] = {
    'created'    => part[0].sub(/\w{2}   /,'').strip,
    'sequence'   => part[1].sub(/\w{2}   /,'').strip,
    'annotation' => part[2].sub(/\w{2}   /,'').strip
  }
end

embl_dr(key = nil)

Backup Bio::EMBLDB#dr as #embl_dr

Alias for: dr

entry()

Alias for: entry_id

entry_id() click to toggle source

returns a ENTRY_NAME in the ID line.

# File lib/bio/db/embl/uniprotkb.rb, line 98
def entry_id
  id_line('ENTRY_NAME')
end

Also aliased as: entry_name, entry

entry_name()

Alias for: entry_id

ft(feature_key = nil) click to toggle source

returns contents in the feature table.

Examples¶ ↑

sp = Bio::UniProtKB.new(entry)
ft = sp.ft
ft.class #=> Hash
ft.keys.each do |feature_key|
  ft[feature_key].each do |feature|
    feature['From'] #=> '1'
    feature['To']   #=> '21'
    feature['Description'] #=> ''
    feature['FTId'] #=> ''
    feature['diff'] #=> []
    feature['original'] #=> [feature_key, '1', '21', '', '']
  end
end

#ft -> Hash

{FEATURE_KEY => [{'From' => int, 'To' => int, 
                  'Description' => aStr, 'FTId' => aStr,
                  'diff' => [original_residues, changed_residues],
                  'original' => aAry }],...}

returns an Array of the information about the feature_name in the feature table.

#ft -> Array of Hash

[{'From' => str, 'To' => str, 'Description' => str, 'FTId' => str},...]

FT Line; feature table data (>=0, optional)¶ ↑

Col     Data item
-----   -----------------
 1- 2   FT
 6-13   Feature name 
15-20   `FROM' endpoint
22-27   `TO' endpoint
35-75   Description (>=0 per key)
-----   -----------------

Note: 'FROM' and 'TO' endopoints are allowed to use non-numerial charactors including '<', '>' or '?'. (c.f. '<1', '?42')

# File lib/bio/db/embl/uniprotkb.rb, line 1196
def ft(feature_key = nil)
  return ft[feature_key] if feature_key
  return @data['FT'] if @data['FT']

  table = []
  begin
    get('FT').split("\n").each do |line|
      if line =~ /^FT   \w/
        feature = line.chomp.ljust(74)
        table << [feature[ 5..12].strip,   # Feature Name
                  feature[14..19].strip,   # From
                  feature[21..26].strip,   # To
                  feature[34..74].strip ]  # Description
      else
        table.last << line.chomp.sub!(/^FT +/, '')
      end
    end

    # Joining Description lines
    table = table.map { |feature| 
      ftid = feature.pop if feature.last =~ /FTId=/
      if feature.size > 4
        feature = [feature[0], 
                   feature[1], 
                   feature[2], 
                   feature[3, feature.size - 3].join(" ")]
      end
      feature << if ftid then ftid else '' end
    }

    hash = {}
    table.each do |feature|
      hash[feature[0]] = [] unless hash[feature[0]]
      hash[feature[0]] << {
        # Removing '<', '>' or '?' in FROM/TO endopoint.
        'From' => feature[1].sub(/\D/, '').to_i,  
        'To'   => feature[2].sub(/\D/, '').to_i, 
        'Description' => feature[3], 
        'FTId' => feature[4].to_s.sub(/\/FTId=/, '').sub(/\.$/, ''),
        'diff' => [],
        'original' => feature
      }

      case feature[0]
      when 'VARSPLIC', 'VARIANT', 'VAR_SEQ', 'CONFLICT'
        case hash[feature[0]].last['Description']
        when /(\w[\w ]*\w*) - ?> (\w[\w ]*\w*)/
          original_res = $1
          changed_res = $2
          original_res = original_res.gsub(/ /,'').strip
          chenged_res = changed_res.gsub(/ /,'').strip
        when /Missing/i
          original_res = seq.subseq(hash[feature[0]].last['From'],
                                    hash[feature[0]].last['To'])
          changed_res = ''
        end
        hash[feature[0]].last['diff'] = [original_res, chenged_res]
      end
    end
  rescue
    raise "Invalid FT Lines(#{$!}) in #{entry_id}:, \n'#{self.get('FT')}'\n"
  end

  @data['FT'] = hash
end

gene_name() click to toggle source

returns a String of the first gene name in the GN line.

# File lib/bio/db/embl/uniprotkb.rb, line 437
def gene_name
  (x = self.gene_names) ? x.first : nil
end

gene_names() click to toggle source

returns a Array of gene names in the GN line.

# File lib/bio/db/embl/uniprotkb.rb, line 426
def gene_names
  gn # set @data['GN'] if it hasn't been already done
  if @data['GN'].first.class == Hash then
    @data['GN'].collect { |element| element[:name] }
  else
    @data['GN'].first
  end
end

gn() click to toggle source

returns gene names in the GN line.

New UniProt/SwissProt format:

#gn -> [ <gene record>* ]

where <gene record> is:

{ :name => '...', 
  :synonyms => [ 's1', 's2', ... ],
  :loci   => [ 'l1', 'l2', ... ],
  :orfs     => [ 'o1', 'o2', ... ] 
}

Old format:

#gn -> Array # AND
#gn -> Array # OR

GN Line: Gene name(s) (>=0, optional)¶ ↑

# File lib/bio/db/embl/uniprotkb.rb, line 350
def gn
  unless @data['GN']
    case fetch('GN')
    when /Name=/,/ORFNames=/,/OrderedLocusNames=/,/Synonyms=/
      @data['GN'] = gn_uniprot_parser
    else
      @data['GN'] = gn_old_parser
    end
  end
  @data['GN']
end

hi() click to toggle source

The HI line¶ ↑

#hi #=> hash

# File lib/bio/db/embl/uniprotkb.rb, line 690
def hi
  unless @data['HI']
    @data['HI'] = []
    fetch('HI').split(/\. /).each do |hlist|
      hash = {'Category' => '',  'Keywords' => [], 'Keyword' => ''}
      hash['Category'], hash['Keywords'] = hlist.split(': ')
      hash['Keywords'] = hash['Keywords'].split('; ')
      hash['Keyword'] = hash['Keywords'].pop
      hash['Keyword'].sub!(/\.$/, '')
      @data['HI'] << hash
    end
  end
  @data['HI']
end

id_line(key = nil) click to toggle source

returns a Hash of the ID line.

returns a content (Int or String) of the ID line by a given key. Hash keys: ['ENTRY_NAME', 'DATA_CLASS', 'MODECULE_TYPE', 'SEQUENCE_LENGTH']

ID Line (since UniProtKB release 9.0 of 31-Oct-2006)¶ ↑

ID   P53_HUMAN               Reviewed;         393 AA.
#"ID  #{ENTRY_NAME} #{DATA_CLASS}; #{SEQUENCE_LENGTH}."

Examples¶ ↑

obj.id_line  #=> {"ENTRY_NAME"=>"P53_HUMAN", "DATA_CLASS"=>"Reviewed", 
                  "SEQUENCE_LENGTH"=>393, "MOLECULE_TYPE"=>nil}

obj.id_line('ENTRY_NAME') #=> "P53_HUMAN"

ID Line (older style)¶ ↑

ID   P53_HUMAN      STANDARD;      PRT;   393 AA.
#"ID  #{ENTRY_NAME} #{DATA_CLASS}; #{MOLECULE_TYPE}; #{SEQUENCE_LENGTH}."

Examples¶ ↑

obj.id_line  #=> {"ENTRY_NAME"=>"P53_HUMAN", "DATA_CLASS"=>"STANDARD", 
                  "SEQUENCE_LENGTH"=>393, "MOLECULE_TYPE"=>"PRT"}

obj.id_line('ENTRY_NAME') #=> "P53_HUMAN"

# File lib/bio/db/embl/uniprotkb.rb, line 73
def id_line(key = nil)
  return id_line[key] if key
  return @data['ID'] if @data['ID']

  part = @orig['ID'].split(/ +/)         
  if part[4].to_s.chomp == 'AA.' then
    # after UniProtKB release 9.0 of 31-Oct-2006
    # (http://www.uniprot.org/docs/sp_news.htm)
    molecule_type   = nil
    sequence_length = part[3].to_i
  else
    molecule_type   = part[3].sub(/;/,'')
    sequence_length = part[4].to_i
  end
  @data['ID'] = {
    'ENTRY_NAME'      => part[1],
    'DATA_CLASS'      => part[2].sub(/;/,''),
    'MOLECULE_TYPE'   => molecule_type,
    'SEQUENCE_LENGTH' => sequence_length
  }
end

molecule() click to toggle source

returns a MOLECULE_TYPE in the ID line.

A short-cut for #id_line('MOLECULE_TYPE').

# File lib/bio/db/embl/uniprotkb.rb, line 108
def molecule
  id_line('MOLECULE_TYPE')
end

Also aliased as: molecule_type

molecule_type()

Alias for: molecule

oh() click to toggle source

The OH Line; ¶ ↑

OH NCBI_TaxID=TaxID; HostName. br.expasy.org/sprot/userman.html#OH_line

# File lib/bio/db/embl/uniprotkb.rb, line 520
def oh
  unless @data['OH']
    @data['OH'] = fetch('OH').split("\. ").map {|x|
      if x =~ /NCBI_TaxID=(\d+);/
        taxid = $1
      else
        raise ArgumentError, ["Error: Invalid OH line format (#{self.entry_id}):",
                              $!, "\n", get('OH'), "\n"].join
        
      end
      if x =~ /NCBI_TaxID=\d+; (.+)/ 
        host_name = $1
        host_name.sub!(/\.$/, '')
      else
        host_name = nil
      end
      {'NCBI_TaxID' => taxid, 'HostName' => host_name}
    }
  end
  @data['OH']
end

os(num = nil) click to toggle source

returns a Array of Hashs or a String of the OS line when a key given.

Bio::EMBLDB#os -> Array

[{'name' => '(Human)', 'os' => 'Homo sapiens'}, 
 {'name' => '(Rat)', 'os' => 'Rattus norveticus'}]

Bio::EPTR#os -> Hash

{'name' => "(Human)", 'os' => 'Homo sapiens'}

#os['name'] -> “(Human)”
Bio::EPTR#os(0) -> “Homo sapiens (Human)”

OS Line; organism species (>=1)¶ ↑

OS   Genus species (name).
OS   Genus species (name0) (name1).
OS   Genus species (name0) (name1).
OS   Genus species (name0), G s0 (name0), and G s (name0) (name1).
OS   Homo sapiens (Human), and Rarrus norveticus (Rat)
OS   Hippotis sp. Clark and Watts 825.
OS   unknown cyperaceous sp.

# File lib/bio/db/embl/uniprotkb.rb, line 459
def os(num = nil)
  unless @data['OS']
    os = Array.new
    fetch('OS').split(/, and|, /).each do |tmp|
      if tmp =~ /(\w+ *[\w \:\\+\-\.]+[\w\.])/
        org = $1
        tmp =~ /(\(.+\))/ 
        os.push({'name' => $1, 'os' => org})
      else
        raise "Error: OS Line. #{$!}\n#{fetch('OS')}\n"
      end
    end
    @data['OS'] = os
  end

  if num
    # EX. "Trifolium repens (white clover)"
    return "#{@data['OS'][num]['os']} #{@data['OS'][num]['name']}"
  else
    return @data['OS']
  end
end

ox() click to toggle source

returns a Hash of oraganism taxonomy cross-references.

#ox -> Hash

{'NCBI_TaxID' => ['1234','2345','3456','4567'], ...}

OX Line; organism taxonomy cross-reference (>=1 per entry)¶ ↑

OX   NCBI_TaxID=1234;
OX   NCBI_TaxID=1234, 2345, 3456, 4567;

# File lib/bio/db/embl/uniprotkb.rb, line 503
def ox
  unless @data['OX']
    tmp = fetch('OX').sub(/\.$/,'').split(/;/).map { |e| e.strip }
    hsh = Hash.new
    tmp.each do |e|
      db,refs = e.split(/=/)
      hsh[db] = refs.split(/, */)
    end
    @data['OX'] = hsh
  end
  return @data['OX']
end

protein_name() click to toggle source

returns the proposed official name of the protein. Returns a String.

Since UniProtKB release 14.0 of 22-Jul-2008, the DE line format have been changed. The method returns the full name which is taken from “RecName: Full=” or “SubName: Full=” line normally in the beginning of the DE lines. Unlike parser for old format, no special treatments for fragment or precursor.

For old format, the method parses the DE lines and returns the protein name as a String.

DE Line; description (>=1)¶ ↑

"DE #{OFFICIAL_NAME} (#{SYNONYM})"
"DE #{OFFICIAL_NAME} (#{SYNONYM}) [CONTEINS: #1; #2]."
OFFICIAL_NAME  1/entry
SYNONYM        >=0
CONTEINS       >=0

# File lib/bio/db/embl/uniprotkb.rb, line 250
def protein_name
  @data['DE'] ||= parse_DE_line_rel14(get('DE'))
  parsed_de_line = @data['DE']
  if parsed_de_line then
    # since UniProtKB release 14.0 of 22-Jul-2008
    name = nil
    parsed_de_line.each do |a|
      case a[0]
      when 'RecName', 'SubName'
        if name_pair = a[1..-1].find { |b| b[0] == 'Full' } then
          name = name_pair[1]
          break
        end
      end
    end
    name = name.to_s
  else
    # old format (before Rel. 13.x)
    name = ""
    if de_line = fetch('DE') then
      str = de_line[/^[^\[]*/] # everything preceding the first [ (the "contains" part)
      name = str[/^[^(]*/].strip
      name << ' (Fragment)' if str =~ /fragment/i
    end
  end
  return name
end

ref() click to toggle source

returns contents in the R lines.

Bio::EMBLDB::Common#ref -> [ <refernece information Hash>* ]

where <reference information Hash> is:

{'RN' => '', 'RC' => '', 'RP' => '', 'RX' => '', 
 'RA' => '', 'RT' => '', 'RL' => '', 'RG' => ''}

R Lines

RN RC RP RX RA RT RL RG

# File lib/bio/db/embl/uniprotkb.rb, line 556
def ref
  unless @data['R']
    @data['R'] = [get('R').split(/\nRN   /)].flatten.map { |str|
      hash = {'RN' => '', 'RC' => '', 'RP' => '', 'RX' => '', 
             'RA' => '', 'RT' => '', 'RL' => '', 'RG' => ''}
      str = 'RN   ' + str unless /^RN   / =~ str

      str.split("\n").each do |line|
        if /^(R[NPXARLCTG])   (.+)/ =~ line
          hash[$1] += $2 + ' '
        else
          raise "Invalid format in R lines, \n[#{line}]\n"
        end
      end

      hash['RN'] = set_RN(hash['RN'])
      hash['RC'] = set_RC(hash['RC'])
      hash['RP'] = set_RP(hash['RP'])
      hash['RX'] = set_RX(hash['RX'])
      hash['RA'] = set_RA(hash['RA'])
      hash['RT'] = set_RT(hash['RT'])
      hash['RL'] = set_RL(hash['RL'])
      hash['RG'] = set_RG(hash['RG'])

      hash
    }

  end
  @data['R']
end

references() click to toggle source

returns Bio::Reference object from Bio::EMBLDB::Common#ref.

Bio::EMBLDB::Common#ref -> Bio::References

# File lib/bio/db/embl/uniprotkb.rb, line 650
def references
  unless @data['references']
    ary = self.ref.map {|ent|
      hash = Hash.new('')
      ent.each {|key, value|
        case key
        when 'RA'
          hash['authors'] = value.split(/, /)
        when 'RT'
          hash['title'] = value
        when 'RL'
          if value =~ /(.*) (\d+) \((\d+)\), (\d+-\d+) \((\d+)\)$/
            hash['journal'] = $1
            hash['volume']  = $2
            hash['issue']   = $3
            hash['pages']   = $4
            hash['year']    = $5
          else
            hash['journal'] = value
          end
        when 'RX'  # PUBMED, MEDLINE, DOI
          value.each do |tag, xref|
            hash[ tag.downcase ]  = xref
          end
        end
      }
      Reference.new(hash)
    }
    @data['references'] = References.new(ary)
  end
  @data['references']
end

seq() click to toggle source

returns a Bio::Sequence::AA of the amino acid sequence.

#seq -> Bio::Sequence::AA

blank Line; sequence data (>=1)

# File lib/bio/db/embl/uniprotkb.rb, line 1306
def seq
  unless @data['']
    @data[''] = Sequence::AA.new( fetch('').gsub(/ |\d+/,'') )
  end
  return @data['']
end

Also aliased as: aaseq

sequence_length() click to toggle source

returns a SEQUENCE_LENGTH in the ID line.

A short-cut for #id_line('SEQUENCE_LENGHT').

# File lib/bio/db/embl/uniprotkb.rb, line 117
def sequence_length
  id_line('SEQUENCE_LENGTH')
end

Also aliased as: aalen

set_RN(data) click to toggle source

# File lib/bio/db/embl/uniprotkb.rb, line 587
def set_RN(data)
  data.strip
end

sq(key = nil) click to toggle source

returns a Hash of conteins in the SQ lines.

Bio::UniProtKBL#sq -> hsh

returns a value of a key given in the SQ lines.

Bio::UniProtKBL#sq(key) -> int or str
Keys: ['MW', 'mw', 'molecular', 'weight', 'aalen', 'len', 'length',
```
'CRC64']
```

SQ Line; sequence header (1/entry)¶ ↑

SQ   SEQUENCE   233 AA;  25630 MW;  146A1B48A1475C86 CRC64;
SQ   SEQUENCE  \d+ AA; \d+ MW;  [0-9A-Z]+ CRC64;

MW, Dalton unit. CRC64 (64-bit Cyclic Redundancy Check, ISO 3309).

# File lib/bio/db/embl/uniprotkb.rb, line 1278
def sq(key = nil)
  unless @data['SQ']
    if fetch('SQ') =~ /(\d+) AA\; (\d+) MW; (.+) CRC64;/
      @data['SQ'] = { 'aalen' => $1.to_i, 'MW' => $2.to_i, 'CRC64' => $3 }
    else
      raise "Invalid SQ Line: \n'#{fetch('SQ')}'"
    end
  end

  if key
    case key
    when /mw/, /molecular/, /weight/
      @data['SQ']['MW']
    when /len/, /length/, /AA/
      @data['SQ']['aalen']
    else
      @data['SQ'][key]
    end
  else 
    @data['SQ']
  end
end

synonyms() click to toggle source

returns synonyms (unofficial and/or alternative names). Returns an Array containing String objects.

Since UniProtKB release 14.0 of 22-Jul-2008, the DE line format have been changed. The method returns the full or short names which are taken from “RecName: Short=”, “RecName: EC=”, and AltName lines, except after “Contains:” or “Includes:”. For keeping compatibility with old format parser, “RecName: EC=N.N.N.N” is reported as “EC N.N.N.N”. In addition, to prevent confusion, “Allergen=” and “CD_antigen=” prefixes are added for the corresponding fields.

For old format, the method parses the DE lines and returns synonyms. synonyms are each placed in () following the official name on the DE line.

# File lib/bio/db/embl/uniprotkb.rb, line 293
def synonyms
  ary = Array.new
  @data['DE'] ||= parse_DE_line_rel14(get('DE'))
  parsed_de_line = @data['DE']
  if parsed_de_line then
    # since UniProtKB release 14.0 of 22-Jul-2008
    parsed_de_line.each do |a|
      case a[0]
      when 'Includes', 'Contains'
        break #the each loop
      when 'RecName', 'SubName', 'AltName'
        a[1..-1].each do |b|
          if name = b[1] and b[1] != self.protein_name then
            case b[0]
            when 'EC'
              name = "EC " + b[1]
            when 'Allergen', 'CD_antigen'
              name = b[0] + '=' + b[1]
            else
              name = b[1]
            end
            ary.push name
          end
        end
      end #case a[0]
    end #parsed_de_line.each
  else
    # old format (before Rel. 13.x)
    if de_line = fetch('DE') then
      line = de_line.sub(/\[.*\]/,'') # ignore stuff between [ and ].  That's the "contains" part
    line.scan(/\([^)]+/) do |synonym| 
      unless synonym =~ /fragment/i then 
        ary << synonym[1..-1].strip # index to remove the leading (  
      end
      end
    end
  end
  return ary
end

Description¶ ↑

Examples¶ ↑

References¶ ↑

Public Instance Methods

CC lines (>=0, optional)¶ ↑

DT Line; date (3/entry)¶ ↑

Old format of DT Line; date (3/entry)¶ ↑

Examples¶ ↑

FT Line; feature table data (>=0, optional)¶ ↑

GN Line: Gene name(s) (>=0, optional)¶ ↑

The HI line¶ ↑

ID Line (since UniProtKB release 9.0 of 31-Oct-2006)¶ ↑

Examples¶ ↑

ID Line (older style)¶ ↑

Examples¶ ↑

The OH Line; ¶ ↑

OS Line; organism species (>=1)¶ ↑

OX Line; organism taxonomy cross-reference (>=1 per entry)¶ ↑

DE Line; description (>=1)¶ ↑

SQ Line; sequence header (1/entry)¶ ↑